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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4044e6500d04eba390fd9d9276fdcd70d4f8a88f0d82d50a802680ac278530e0' 
  AND token = 'bORw57a0a5FxJBPEZJuSAd0Cm1EYdoFo+qDiM3Kw/bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}