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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f64180c7eee8862ad7ea2f2f5b5bfa26657270bb8b2cbcfe3fd3da3b69d782d5' 
  AND token = '8O28oxS+VFUmhUZPpYxZN0FjT7UyCGe6cvFDeF1W+qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}