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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '816b3373afa18bbf47fb2496a7ac538075bb006105fe4348d92fdf949bade6c2' 
  AND token = 'L7GOg0a+MCDVAxUf8AneBhA8Zg1S6I1I4Lxxyb3NZsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}