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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '642b5b18d88d4191faf18257f1a192b5a89b5a0c4120fc7772c5107dda971e22' 
  AND token = 'lwfLT5PFbPDpM37V71otplw7TxfBi7s3ngiqYNewTno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}