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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed100e8eafd31ead2fc3f842b4842586b8e635f89d7155124c5e80f9f0750ac7' 
  AND token = '+06gUBP0fLXyMVsp5U7v73rxB3RvZTIemUPh5PPFFV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}