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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd44e110bbdf308806c4370e1fb6aa80e7c633b4a7cc88b603eb3340bd9f3da37' 
  AND token = 'tYyXSYbV54y55Sp4nhsblskkqAR/KC8Y29MQvqB7NDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}