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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '725b888abbf5603f2bb1ad3f7dffb1c7f19f66fd33bf2c283748afd3e62703ab' 
  AND token = 'vKuyuCGxCJLf9vAKsZWBxy0RsGWHezyOJuMB+W4kGuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}