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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e83088bf493452f2378cc5ab54da021f15254cbf0375216be415a81a87e6223' 
  AND token = 'PC6GqS39aeBfU3t4PKcL5hhrXp+9MThgfxdKG7gQwME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}