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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e081fb5ba1fa09994aba80fc4938afdb17a4118b9ba31ccd9db9a40a73cf125c' 
  AND token = 'K2oCOKOL9uuJdY+HgtmZnvohSMXYAXhW2e30w0UiQec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}