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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d413002bfb0cddf11f648509ba024a7982132d36cb3fdb215b2a7e0521adef4' 
  AND token = 'riNTp+EE+l2j+0PqXOHY+H74lLR5UDTXdHeWWWF4AP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}