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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49352df7806752ad32fa0a926a8d8d753a8852f2d30e009f61060d0c385bc14e' 
  AND token = '1nzo/zZLA9RpKfe4YDULTvFw1kMaB2DFD5iOOX7IikU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}