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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c7802e457e761699b267fa3b59e4ca66915676fd3a271013ede5f06b71ac790' 
  AND token = 'uXWlLEYEH9lRPxuJ+a6wnp1lt7jS0UtJGqNrRozCfGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}