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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2877459591cc401e2f51ae173618b4cd4f681f0b948302bfe2730c5fccd6dd72' 
  AND token = '+kR47+EVZdS0toIYfDlVJqTpNlrO3djG4/6aqfWMhH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}