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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '144df0a4bf647000173fa00aa3e3189d43ba7f519a3200cba77b41d5f67f4d66' 
  AND token = 'ToIMrzLJorSiUcE7xAk1XTZMw2OBszmWsL/IUttL+1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}