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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '375b5f2e442c2cff7675f1b5798949462857d3fdf97acef7c107db25fe23e044' 
  AND token = 'rR0YpMnWipEeb2CRNxdzkXEz/z19glIK/9aEkaBW69o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}