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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '208b3b197890a992bb0a244e17d057fb18034adc0ac26c4202cd7a87e7a84e2c' 
  AND token = 'rJVJn6ZEa1YK+8msj/laEOwvmSMCdpMv6lq2/QkTgdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}