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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489438a78c31a3119dd050977cded8dbbb6d1c356e203fe4edb37d564840bd17' 
  AND token = '6jgi8oxEDSDeg3OxEXzqamZMDoxRk+dn90aEP8GHFz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}