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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '669aa78f1dbb162af25815dcd35f07d6f06ec06d7775a43f1f2a3ee3b9a7eccb' 
  AND token = '7DZ3F9xOMlzM9iD5S7Y+uvhA8L1YihiUgQLmdezawS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}