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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fc285fc2ef84891782cbd16e93001fe1ca7648f9fc9b0bf4737a5ead090ef0b' 
  AND token = '2xXf5xTSoB5CfqRZcUNyUjiR3U9DrbHCJjpKWD9n4Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}