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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e7a1fd094464f85621a3033eaf19d17896e100bab9228640cb17cb523df64d' 
  AND token = 'bAObH5N1Sl+RKK3b0tHjbRBdErJEFTCYsyT7QcrMaqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}