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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '975f4d8b42946878bcc95825ccd6df8b9dd8a9b4efab61c7cccd6a1e764af48f' 
  AND token = 'Eupo2xqBfTty1PXg9W4jgtqkifBG/ccm5Bm+zzev/M4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}