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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e1a744c83dee417c3e358de7969def9078d6e3b11aab3a2fa3d5f49bcbcd09' 
  AND token = 'yf+FhpF2kCJIHRKNjZsyH7MH+cCcJxjbLXS6TUOoXcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}