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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0ed300deca30f976104037dcf1f02dd110db88fbc05c3812121829fc401f91b' 
  AND token = 'IVn15Y+W4Oct9y7PD27u8L9tnSNmx3LOVK3VwrqjkjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}