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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5357ce3d15f321c446c9f20142295f2e83263d4e67969d6b5cc6e7cb08225dae' 
  AND token = 'nRXAIUkQGI++e2EJMsqIIouPTtf/K5gLSV/5zM70iqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}