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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100fcb600860159af666bfd8fc7c3277c39a272f5e2946a0b2e4f387b46ddd06' 
  AND token = 'i2xy01h+DlOFaP65OdW3vAF9+fwUq0fID/oE8PihjvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}