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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ef482e4ee49e3c0b9c7026d555af6a7e89cad1ed68512c6cda595c3960a777' 
  AND token = 'eT9h+KcDs2EKJ/gwGxQQ/5N9D4G+PmGqMlKqKHGkXRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}