SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2be1f9def59a487fda6f15424d8ac51c72e3e57de8062753ae3813e4685b7dd9' 
  AND token = 'Ss1jfRyqp3/hsoBMhIFsy/cSeMgiZE7JhnbsPpdIeZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}