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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa6f0dea25cb24d6b240099bdb11148a216adde2fa593936102f276d32fe53c' 
  AND token = 'U0/978RsPGH7FltN+/AVntplL6fZave7MsBn25e4zXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}