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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f04b25b4d0da4d67bda1fec2f1c3926e64843e2123d28cd44aab0e8eca7ed5' 
  AND token = 'EkM01EKLorCY8aKYwKi1nVGM9IYk6R5hi0vkPUyd64Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}