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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b78728ac5071afc364cd1e620e95dd2b544f16d841389bb5c259b2bfb548b25a' 
  AND token = 'Z6r7Vvi+sBbkYB+M0hGdSFt2/iW1/+DRB7uM47Fn2/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}