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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621414083c229389d9798144b51170f45297d9907cf3b9ea9098fe4b5afca30b' 
  AND token = '6xbnlZxlTzTVkldRKhleUf+APqK+3skaQH4ycfnROjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}