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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c252d42984fbba00abc618ebb5e7ade481571899704e651f9863c0e0c0cd01c6' 
  AND token = 'rOHEXzoT9SEy5WOW3YAPaQeWW/vEcjDC+1CGez/DQow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}