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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '065162ec08fa86966bcc8ae6afb2e25d81867a924670097b54a0268a377f2b46' 
  AND token = 'uLp55WreaPOat/nFZznUmEQ2ovkf4Wc8oo34YV4/Ahk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}