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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53a5c838d0097ca08aec5c3b081fa57c802867a08b4cd36e5abd604bd4180556' 
  AND token = 'xVn0L9UJyt5ILIKVJBYKH6H0XR//4wYR0Okv8MkoMlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}