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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a1e457b42daa7d52b168e905fc85e7409d2d87a835ba0585a8b16a0f62e9c55' 
  AND token = 'RSWATTcIzCWB9uj/Rh+gq1ombha7h0LARag+FM3kIiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}