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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e4326fd621a095e2980bd87de4e9a347aed64de2a2e6d0b446b4e94de02161' 
  AND token = 'sFPByzhp36UYIb0Pnzxb/xtZT4yVxWbOvxflw/LFPCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}