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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649b1976db52227acd2a082a42f22ad2350f4bf20dab7af8e128cbca56a3869f' 
  AND token = 'XOVuAbCsjUCToARJvu37Rncuq9TzLR30x4YXLBO36RI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}