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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4305aaca72b9c8fdf3cb887514add4038e8d2e2d31ade95a434f02a1dbc00cf' 
  AND token = 'O+lx7gxyPf9AnTmIkwPSmCa3nqReWmDvGP+FwKgA340=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}