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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b2666656d286c09845193e0a5a9e6c715b4c69f41dc7cd98b3907e24b00b37' 
  AND token = 'vAoYqh727PIpVazZ1OtHUs0QGQifVaMbNXTezjoxnto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}