SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ac6cdf9981350bec8f7a0f834a04b249281a968b4ad523f23a7de0eb83ec6a6' 
  AND token = '/8XcjyT+6s1l5lZrcYSiPPF7igPSrpDaCZ4lJxtkc/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}