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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e550f2427461db398641b923182537f89ce0b45ff89c1751a8069b57f3a20d8c' 
  AND token = 'TffFtJVL3kb2t8MENS64NIDu2O519ggsM12+OWsIAvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}