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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2e74bc2af0b9b5ee56de99d0ff162fdb53d300946ce90bf65b517594609787' 
  AND token = 'oB6vWUnQFzpwoQbXtIcLmbXOdrj/8h5A2xqX4RBxiY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}