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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a460437be7e94907a8e96e4b342e5b3d400fd62b3eb6f3211faaeeb69f6c9d26' 
  AND token = 'aI3Jx+RmjxkcycnQX8e5XN6RCvTYzoRrkBsfbQwdeS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}