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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cbe09b3ea3148c58c97aa020271c4b1e40f4d696b8f7c7c32f7468edffa07d5' 
  AND token = '2U0ejJh3469ft+z92OgrCXfTf/3GhHwWoxKCG68+RN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}