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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b57b8d12e08e062c4fe6511f0c7c5121ba62daf3a05e52e4b2931596664a84b3' 
  AND token = 'Ve0YzDUDrgE7Lc306ksEKYO/4955puiYC5L4vEDvhc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}