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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280d77f3be47ee3a2c968168bbcf01376610ecace53cf5d17f6e3385980fa9c7' 
  AND token = '/R9bZlpXKiyvelpS4X/68LD0iDWSYzbs8JcDVdCSdrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}