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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51144f9efdfc52549c926c61a311c175d5a56a3a385124f3bdb06e06a75ca0e0' 
  AND token = 'aXgaeTsdSBLlLUFuM1Bq8SbKHj6P8JuOuwxcmjd2T8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}