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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cd03a3fdb7c897931d7a3547069a3cd7071abd1d8a612067d0a8050019d0a8c' 
  AND token = '2H6QuTT8hFXIHCEM9cTk3Q+a4o+WpJiu5eBj2a4Jjzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}