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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cae48a7770af9988aacfb874a82d1b4244faf83b5badbc23b4a16eebf3c78b43' 
  AND token = 'mDmzwEOS1RgVtpdtwpDWXSFZmBxGB+/tX1xH288VF74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}