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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f7c3abbb9ba48d155215b959a84f619d03f5925b058f2bdb7df7d1063a1609' 
  AND token = 'yuosF4PyOE0tsYnXmxLxMfdX4V5Q+lUye5TTI6HkTK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}